Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
p4ha3Prolyl 4-hydroxylase, alpha polypeptide III. (542 aa)    
Predicted Functional Partners:
pycr3
Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.
     
 0.931
LOC101175323
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
   
 
 0.907
LOC101165161
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
   
 
 0.907
prodh2
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
   
 
 0.907
LOC101172166
Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.
     
 0.906
LOC101156872
Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family.
     
 0.906
lap3
Leucine aminopeptidase 3.
     
 0.902
p4hb
Protein disulfide-isomerase.
   
 0.835
LOC101164281
Protein disulfide-isomerase.
   
 0.835
dao
D-amino-acid oxidase, tandem duplicate 2.
     
 0.802
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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