STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MPDZMultiple PDZ domain crumbs cell polarity complex component. (1695 aa)    
Predicted Functional Partners:
mpp5
Membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5); Belongs to the MAGUK family.
    
 0.755
MPP5
Membrane palmitoylated protein 5; Belongs to the MAGUK family.
    
 0.755
ift57
Intraflagellar transport 57 homolog (Chlamydomonas).
    
 0.589
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
   0.584
traf3ip1
TNF receptor-associated factor 3 interacting protein 1.
    
 0.583
ift80
Intraflagellar transport 80 homolog (Chlamydomonas).
   
 0.577
ift172
Intraflagellar transport 172.
    
 0.572
LOC101172563
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
   
 0.559
cask
Uncharacterized protein; Belongs to the MAGUK family.
   
 0.559
prkci
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    
 0.546
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.