tgs1 protein (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

tgs1

LYN proto-oncogene, Src family tyrosine kinase. (809 aa)

Predicted Functional Partners:

snrpe

0.982

snrpg

0.975

snrpd2

0.970

ncoa6

0.829

gemin2

0.789

snrpd3

0.789

naa38

0.779

spaca6

0.779

ddx20

0.744

u2af2

0.722

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ddx20	gemin2	ENSORLP00000011224	ENSORLP00000022112	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family.	0.935
ddx20	naa38	ENSORLP00000011224	ENSORLP00000008932	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.	N(alpha)-acetyltransferase 38, NatC auxiliary subunit.	0.662
ddx20	snrpd2	ENSORLP00000011224	ENSORLP00000043777	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.	Small nuclear ribonucleoprotein Sm D2.	0.773
ddx20	snrpd3	ENSORLP00000011224	ENSORLP00000030977	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.	Small nuclear ribonucleoprotein Sm D3.	0.894
ddx20	snrpe	ENSORLP00000011224	ENSORLP00000029192	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.815
ddx20	snrpg	ENSORLP00000011224	ENSORLP00000030086	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.	Small nuclear ribonucleoprotein G.	0.886
ddx20	spaca6	ENSORLP00000011224	ENSORLP00000028234	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.	Ig-like domain-containing protein.	0.662
ddx20	tgs1	ENSORLP00000011224	ENSORLP00000005385	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.	LYN proto-oncogene, Src family tyrosine kinase.	0.744
ddx20	u2af2	ENSORLP00000011224	ENSORLP00000014464	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.	0.422
gemin2	ddx20	ENSORLP00000022112	ENSORLP00000011224	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.	0.935
gemin2	snrpd2	ENSORLP00000022112	ENSORLP00000043777	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family.	Small nuclear ribonucleoprotein Sm D2.	0.995
gemin2	snrpd3	ENSORLP00000022112	ENSORLP00000030977	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family.	Small nuclear ribonucleoprotein Sm D3.	0.976
gemin2	snrpe	ENSORLP00000022112	ENSORLP00000029192	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.974
gemin2	snrpg	ENSORLP00000022112	ENSORLP00000030086	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family.	Small nuclear ribonucleoprotein G.	0.974
gemin2	tgs1	ENSORLP00000022112	ENSORLP00000005385	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family.	LYN proto-oncogene, Src family tyrosine kinase.	0.789
gemin2	u2af2	ENSORLP00000022112	ENSORLP00000014464	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family.	U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family.	0.404
naa38	ddx20	ENSORLP00000008932	ENSORLP00000011224	N(alpha)-acetyltransferase 38, NatC auxiliary subunit.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.	0.662
naa38	snrpd2	ENSORLP00000008932	ENSORLP00000043777	N(alpha)-acetyltransferase 38, NatC auxiliary subunit.	Small nuclear ribonucleoprotein Sm D2.	0.978
naa38	snrpd3	ENSORLP00000008932	ENSORLP00000030977	N(alpha)-acetyltransferase 38, NatC auxiliary subunit.	Small nuclear ribonucleoprotein Sm D3.	0.977
naa38	snrpe	ENSORLP00000008932	ENSORLP00000029192	N(alpha)-acetyltransferase 38, NatC auxiliary subunit.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.978