Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
spock1SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1. (503 aa)    
Predicted Functional Partners:
adam10
Uncharacterized protein.
     
 0.687
timp-2b
Tissue inhibitor of metalloproteinase-2b.
     
  0.566
timp2
Tissue inhibitor of metalloproteinase-2a.
     
  0.566
mmp15
ZnMc domain-containing protein.
    
 0.564
mmp14
ZnMc domain-containing protein.
    
 0.564
LOC100049402
Somatolactin; Selectively regulates proliferation and morphogenesis of neural-crest derived pigment cells; Belongs to the somatotropin/prolactin family.
    
 0.505
sparc
Osteonectin.
   
  
 0.491
LOC105355780
SPARC-like 2.
   
  
 0.491
fam222a
Family with sequence similarity 222 member A.
      
 0.463
mmp9
Uncharacterized protein.
    
 0.461
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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