STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptch1Patched 1. (1552 aa)    
Predicted Functional Partners:
shh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.995
smo
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.995
dhh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.990
LOC101170159
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.988
LOC100125500
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
 0.988
boc
BOC cell adhesion associated, oncogene regulated.
    
 0.974
cdon
Cell adhesion associated, oncogene regulated.
    
 0.974
H2LCR5_ORYLA
Growth arrest-specific 1b.
     
 0.969
LOC101160323
E3 ubiquitin-protein ligase.
    
 0.964
SMURF2
E3 ubiquitin-protein ligase.
    
 0.964
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.