ptch1 protein (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

ptch1

Patched 1. (1552 aa)

Predicted Functional Partners:

smo

0.997

shh

0.995

dhh

0.990

LOC101170159

0.989

LOC100125500

0.989

boc

0.984

cdon

0.984

LOC101160323

0.975

SMURF2

0.975

smurf1

0.975

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100125500	boc	ENSORLP00000041999	ENSORLP00000011399	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	BOC cell adhesion associated, oncogene regulated.	0.947
LOC100125500	cdon	ENSORLP00000041999	ENSORLP00000031463	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Cell adhesion associated, oncogene regulated.	0.947
LOC100125500	ptch1	ENSORLP00000041999	ENSORLP00000005449	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Patched 1.	0.989
LOC100125500	smo	ENSORLP00000041999	ENSORLP00000018001	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.915
LOC101160323	SMURF2	ENSORLP00000018986	ENSORLP00000035266	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.900
LOC101160323	ptch1	ENSORLP00000018986	ENSORLP00000005449	E3 ubiquitin-protein ligase.	Patched 1.	0.975
LOC101160323	smo	ENSORLP00000018986	ENSORLP00000018001	E3 ubiquitin-protein ligase.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.522
LOC101160323	smurf1	ENSORLP00000018986	ENSORLP00000043009	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.902
LOC101170159	boc	ENSORLP00000002065	ENSORLP00000011399	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	BOC cell adhesion associated, oncogene regulated.	0.947
LOC101170159	cdon	ENSORLP00000002065	ENSORLP00000031463	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Cell adhesion associated, oncogene regulated.	0.947
LOC101170159	ptch1	ENSORLP00000002065	ENSORLP00000005449	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Patched 1.	0.989
LOC101170159	smo	ENSORLP00000002065	ENSORLP00000018001	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.915
SMURF2	LOC101160323	ENSORLP00000035266	ENSORLP00000018986	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.900
SMURF2	ptch1	ENSORLP00000035266	ENSORLP00000005449	E3 ubiquitin-protein ligase.	Patched 1.	0.975
SMURF2	smo	ENSORLP00000035266	ENSORLP00000018001	E3 ubiquitin-protein ligase.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.522
SMURF2	smurf1	ENSORLP00000035266	ENSORLP00000043009	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.902
boc	LOC100125500	ENSORLP00000011399	ENSORLP00000041999	BOC cell adhesion associated, oncogene regulated.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.947
boc	LOC101170159	ENSORLP00000011399	ENSORLP00000002065	BOC cell adhesion associated, oncogene regulated.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.947
boc	cdon	ENSORLP00000011399	ENSORLP00000031463	BOC cell adhesion associated, oncogene regulated.	Cell adhesion associated, oncogene regulated.	0.900
boc	dhh	ENSORLP00000011399	ENSORLP00000009519	BOC cell adhesion associated, oncogene regulated.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.944