Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hsp90b1Heat shock protein 90, beta (grp94), member 1. (796 aa)    
Predicted Functional Partners:
hspa5
Uncharacterized protein; Belongs to the heat shock protein 70 family.
   
 0.999
LOC101169506
Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.
  
0.988
hsp90ab1
Heat shock protein 90, alpha (cytosolic), class B member 1.
  
0.988
pdia6
Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family.
   
 0.985
LOC101162115
Calreticulin.
   
 0.977
LOC101160304
Calreticulin.
   
 0.972
LOC101169735
Calreticulin.
   
 0.972
LOC101175475
Canopy FGF signaling regulator 2.
   
 
 0.969
trap1
TNF receptor-associated protein 1.
  
0.958
ganab
Glucosidase, alpha; neutral AB; Belongs to the glycosyl hydrolase 31 family.
   
 
 0.956
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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