Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ercc3Excision repair cross-complementation group 3. (783 aa)    
Predicted Functional Partners:
gtf2h1
General transcription factor IIH, polypeptide 1.
   
 0.999
gtf2h4
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
  
 0.999
xpa
Xeroderma pigmentosum, complementation group A.
    
 0.999
gtf2h5
General transcription factor IIH, polypeptide 5.
    
 0.999
ercc2
Excision repair cross-complementation group 2.
   
 0.999
gtf2h3
General transcription factor IIH, polypeptide 3.
   
 0.999
mnat1
CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.
    
 0.999
LOC101167715
General transcription factor IIH subunit.
    
 0.999
ccnh
Cyclin H; Belongs to the cyclin family.
    
 0.997
gtf2b
General transcription factor IIB.
    
 0.996
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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