Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC101164953Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (954 aa)    
Predicted Functional Partners:
Kitlg
Kit ligand a.
   
 0.995
LOC105357082
Uncharacterized protein.
     
 0.952
grb2
Growth factor receptor-bound protein 2b.
   
 0.941
kras
GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation.
    
 0.938
hras
HRas proto-oncogene, GTPase a.
    
 0.936
il34
Interleukin 34.
   
 0.931
LOC101168287
Colony stimulating factor 1b (macrophage).
   
 0.911
kit
Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
  
  
0.905
fgf23
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
    
 0.796
LOC101161449
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
    
 0.785
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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