Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
iffo2Intermediate filament family orphan 2b; Belongs to the intermediate filament family. (491 aa)    
Predicted Functional Partners:
aldh4a1
Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
      0.856
mrto4
Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
      
 0.757
LOC101175148
Aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase).
      
 0.739
LOC101166932
X-ray repair complementing defective repair in Chinese hamster cells 4.
    
 
 0.712
tcf19
Transcription factor 19 (SC1), like.
      
 0.560
timp4
TIMP metallopeptidase inhibitor 4, tandem duplicate 2.
      
 0.525
Vamp3
Vesicle-associated membrane protein 3 (cellubrevin).
    
   0.487
LOC101159022
Uncharacterized protein.
    
   0.473
ppard
Uncharacterized protein.
      
 0.464
megf6
Multiple EGF-like-domains 6b.
      
 0.463
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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