Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
klbKlotho beta. (1045 aa)    
Predicted Functional Partners:
fgf23
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
    
 0.876
fgfr1
Fibroblast growth factor receptor.
    
 0.710
LOC100049521
Fibroblast growth factor receptor 4.
    
 0.694
fgf19
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.683
flrt3
Fibronectin leucine rich transmembrane 3.
     
 0.647
fgfr2
Fibroblast growth factor receptor.
    
 0.609
fgfr3
Fibroblast growth factor receptor.
    
 0.609
rps27a
Ribosomal protein S27a.
    
 0.556
LOC101155126
Fibroblast growth factor receptor.
    
 0.554
fgf3
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.514
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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