STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101174465FERM domain-containing protein. (423 aa)    
Predicted Functional Partners:
yap1
Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation.
   
 0.904
mylip
Myosin regulatory light chain interacting protein a.
      
 0.789
fbxw11
F-box and WD repeat domain containing 11a.
    
 
 0.739
ENSORLP00000028654
SUEL-type lectin domain-containing protein.
    
   0.717
ENSORLP00000034371
SUEL-type lectin domain-containing protein.
    
   0.717
LOC101172768
Si:ch1073-186i23.1; Belongs to the G-protein coupled receptor 2 family.
    
   0.717
adgrl2
Adhesion G protein-coupled receptor L2a; Belongs to the G-protein coupled receptor 2 family.
    
   0.717
LOC101166443
Adhesion G protein-coupled receptor L3.1; Belongs to the G-protein coupled receptor 2 family.
    
   0.717
LOC101161954
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
    
   0.717
adgrl1
Adhesion G protein-coupled receptor L1a; Belongs to the G-protein coupled receptor 2 family.
    
   0.717
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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