Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
traf4TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (500 aa)    
Predicted Functional Partners:
usp7
Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.
    
 0.953
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 
 0.918
ncf1
Neutrophil cytosolic factor 1.
   
 
 0.897
psmc3
Proteasome 26S subunit ATPase 3; Belongs to the AAA ATPase family.
    
  0.777
ISYNA1
Inositol-3-phosphate synthase 1.
    
   0.768
LOC101170271
Nerve growth factor receptor a (TNFR superfamily, member 16).
    
 0.762
map3k4
Mitogen-activated protein kinase kinase kinase 4.
    
 
 0.762
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
 0.750
irak4
Interleukin-1 receptor-associated kinase 4.
   
 0.744
usp40
Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family.
    
 0.741
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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