Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101171270RAB38b, member of RAS oncogene family. (218 aa)    
Predicted Functional Partners:
LOC101158129
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.722
vti1a
Vesicle transport through interaction with t-SNAREs 1A.
      
 0.715
gak
Cyclin G associated kinase.
    
 
 0.672
rabggta
Rab geranylgeranyltransferase subunit alpha.
    
  0.638
ankrd27
Ankyrin repeat domain 27 (VPS9 domain).
    
 
 0.617
lta4h
Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family.
      
 0.603
prdx5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
      
 0.499
rabggtb
Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.
     
 0.494
gcnt3
Glucosaminyl (N-acetyl) transferase 3, mucin type.
      
 0.480
st6galnac2
Uncharacterized protein; Belongs to the glycosyltransferase 29 family.
      
 0.480
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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