Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dlx6Distal-less homeobox 6a. (246 aa)    
Predicted Functional Partners:
dlx5
Distal-less homeobox 5a.
  
 
0.881
hand2
Heart and neural crest derivatives expressed 2.
    
 
 0.623
edn1
Endothelin 1.
      
 0.587
bmp4
Bone morphogenetic protein 4.
     
 0.579
hopx
Homeobox domain-containing protein.
     
 0.567
ednra
Endothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family.
      
 0.547
ENSORLP00000027361
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.527
fgf8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.506
ext2
Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.
      
 0.498
LOC101167186
Methyl CpG binding protein 2.
      
 0.498
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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