Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHA5Pleckstrin homology domain containing A5. (1306 aa)    
Predicted Functional Partners:
pdzd11
PDZ domain containing 11.
    
 0.871
LOC105356552
PH domain-containing protein.
    
 0.585
myct1
Myc target 1a.
      
 0.575
rps27a
Ribosomal protein S27a.
    
  0.541
mphosph8
Uncharacterized protein.
    
 
 0.517
actr10
Actin related protein 10; Belongs to the actin family.
    
 
 0.508
lats1
Large tumor suppressor kinase 1.
   
 0.507
lats2
Large tumor suppressor kinase 2.
   
 0.507
sgk3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.494
plekha8
Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8.
      
 0.490
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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