Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ercc8Excision repair cross-complementation group 8. (401 aa)    
Predicted Functional Partners:
ddb1
Damage-specific DNA binding protein 1.
    
 0.999
ercc6
Excision repair cross-complementation group 6.
    
 0.999
uvssa
UV-stimulated scaffold protein A.
    
 0.996
LOC101154851
Cullin 4A; Belongs to the cullin family.
    
 0.995
cops5
COP9 signalosome subunit 5.
   
  0.984
ddb2
Damage-specific DNA binding protein 2.
    
 0.983
COPS6
COP9 signalosome subunit 6.
   
  0.981
cops2
COP9 signalosome subunit 2.
    
 0.975
cul4b
Cullin 4B; Belongs to the cullin family.
    
 0.962
cop1
COP1 E3 ubiquitin ligase.
    
 0.957
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (18%) [HD]