Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC101174595Mitogen-activated protein kinase kinase kinase 14a. (866 aa)    
Predicted Functional Partners:
ikbkb
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
 0.985
LOC101171857
Component of inhibitor of nuclear factor kappa B kinase complex.
   
0.985
LOC101155367
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.983
traf2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.983
LOC101167626
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.983
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
0.979
map3k8
Mitogen-activated protein kinase kinase kinase 8.
    
0.975
map3k7
Mitogen-activated protein kinase kinase kinase 7.
    
 
0.946
ikbkg
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
 0.925
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.915
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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