Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PLCZ1Phosphoinositide phospholipase C. (659 aa)    
Predicted Functional Partners:
ipmk
Kinase; Belongs to the inositol phosphokinase (IPK) family.
    
 0.913
cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
     
 0.907
Itpr2
Inositol 1,4,5-trisphosphate receptor, type 2.
   
 
 0.905
LOC101155104
Inositol 1,4,5-trisphosphate receptor, type 1b.
   
 
 0.905
LOC101167700
Inositol 1,4,5-trisphosphate receptor, type 1a.
   
 
 0.905
itpr3
Inositol 1,4,5-trisphosphate receptor, type 3.
   
 
 0.905
PRKCB
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
   
 0.903
LOC101159746
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
   
 0.903
PRKCA
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
   
 0.903
pikfyve
Phosphoinositide kinase, FYVE finger containing.
     
 0.903
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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