STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101171145Sprouty RTK signaling antagonist 2. (342 aa)    
Predicted Functional Partners:
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase.
    
 0.917
grb2
Growth factor receptor-bound protein 2b.
    
 0.911
LOC101163758
Uncharacterized protein.
    
 0.882
cblb
Cbl proto-oncogene B, E3 ubiquitin protein ligase.
    
 0.882
LOC101158476
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
    
 0.882
braf
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.704
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
    
 0.641
araf
A-Raf proto-oncogene, serine/threonine kinase.
    
 0.641
egf
Epidermal growth factor.
     
 0.630
LOC101166137
EGF-like domain-containing protein.
     
 0.625
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.