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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
abcg8ATP-binding cassette, sub-family G (WHITE), member 8. (653 aa)    
Predicted Functional Partners:
abcg5
ATP-binding cassette, sub-family G (WHITE), member 5.
  
0.998
dhcr7
7-dehydrocholesterol reductase.
   
  
 0.580
nr1h4
Nuclear receptor subfamily 1, group H, member 4.
   
 0.567
LOC100125499
3-hydroxy-3-methylglutaryl coenzyme A reductase.
      
 0.565
hmgcs1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
  
 0.523
LOC101169721
Apolipoprotein A-Ib.
   
 0.506
nr1h3
Nuclear receptor subfamily 1, group H, member 3.
   
 0.499
LOC101160349
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
   
 
 0.497
LOC101166888
3-hydroxy-3-methylglutaryl coenzyme A reductase.
      
 0.483
abcc5
Si:ch211-221f10.2.
  
 0.482
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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