STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smpd1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (604 aa)    
Predicted Functional Partners:
smpd2
Sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase).
     
 0.980
smpd3
Sphingomyelin phosphodiesterase 3, neutral.
     
 0.974
ugcg
UDP-glucose ceramide glucosyltransferase.
     
 0.945
sgms1
Zgc:91976.
     
 0.942
sgms2
Sphingomyelin synthase 2a.
     
 0.942
LOC101170793
PAP2_C domain-containing protein.
     
 0.942
gba
Glucosylceramidase.
   
 
 0.939
galc
Galactosylceramidase b.
     
 0.936
LOC101160838
Sphingomyelin phosphodiesterase 5.
     
 0.930
LOC101165056
Zgc:158263.
    
 0.926
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.