Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
snx8Sorting nexin 8a. (521 aa)    
Predicted Functional Partners:
msh3
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
    
   0.962
igf2r
Insulin-like growth factor 2 receptor.
    
 0.823
snx5
Sorting nexin 5.
   
 0.769
snx6
Sorting nexin; Involved in several stages of intracellular trafficking.
   
 0.756
snx9
Sorting nexin.
   
 0.738
tmem203
Transmembrane protein 203.
      
 0.717
vps29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 
 0.663
vps26a
VPS26, retromer complex component A.
   
 
 0.640
kars1
Lysine--tRNA ligase.
   
   0.630
gak
Cyclin G associated kinase.
   
 
 0.628
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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