Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
itgb3Integrin beta; Belongs to the integrin beta chain family. (795 aa)    
Predicted Functional Partners:
itga8
Integrin, alpha 8; Belongs to the integrin alpha chain family.
   
 0.987
itga3
Integrin, alpha 3b; Belongs to the integrin alpha chain family.
   
 0.980
itgav
Integrin, alpha V; Belongs to the integrin alpha chain family.
   
 0.978
LOC101158275
Integrin, alpha 5 (fibronectin receptor, alpha polypeptide); Belongs to the integrin alpha chain family.
   
 0.972
LOC101157076
Vitronectin b.
    
 0.964
LOC101170202
Vitronectin a.
    
 0.964
ptk2
Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.962
thbs2
Thrombospondin 2a.
   
 0.960
thbs1
Uncharacterized protein.
   
 0.960
LOC100302438
Thrombospondin 1b.
   
 0.960
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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