Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tmco3Transmembrane and coiled-coil domains 3. (670 aa)    
Predicted Functional Partners:
tfdp1
Transcription factor.
 
    
 0.786
pcid2
PCI domain containing 2.
      
 0.762
LOC101169401
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3.
      
 0.726
adprhl1
ADP-ribosylhydrolase like 1.
      
 0.702
naxd
ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
     
 0.648
cars2
Cysteinyl-tRNA synthetase 2, mitochondrial.
     
 0.621
LOC105356552
PH domain-containing protein.
      
 0.604
GRTP1
Growth hormone regulated TBC protein 1b.
      
 0.603
LOC101171119
Growth hormone regulated TBC protein 1b.
      
 0.603
rab20
RAB20, member RAS oncogene family.
      
 0.581
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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