Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gas6Growth arrest-specific 6. (684 aa)    
Predicted Functional Partners:
AXL
AXL receptor tyrosine kinase.
    
 0.987
LOC101158315
TYRO3 protein tyrosine kinase.
    
 0.986
mertk
C-mer proto-oncogene tyrosine kinase a.
    
 0.971
auts2
Activator of transcription and developmental regulator AUTS2 a.
    
 0.942
LOC101164758
Fibrosin.
    
 0.920
LOC101158550
Nucleophosmin 1a.
    
 0.776
med13
Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
     
 0.704
LOC100049240
Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family.
   
 0.688
furin
Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family.
   
 0.688
VMP1
Vacuole membrane protein 1.
      
 0.635
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (26%) [HD]