Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ppargc1aPeroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (1268 aa)    
Predicted Functional Partners:
LOC100125507
Estrogen-related receptor alpha.
   
 0.996
sirt1
Deacetylase sirtuin-type domain-containing protein.
   
 0.964
nrf1
Nuclear respiratory factor 1.
    
 0.953
pparg
Uncharacterized protein.
    
 0.932
PPARA
Peroxisome proliferator-activated receptor alpha b.
    
 0.913
nr1h4
Nuclear receptor subfamily 1, group H, member 4.
    
 0.912
cwc15
CWC15 spliceosome associated protein homolog.
   
 
 0.907
crnkl1
Crooked neck pre-mRNA splicing factor 1.
   
 0.883
bud31
BUD31 homolog.
   
 0.880
xab2
XPA binding protein 2.
   
 0.873
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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