STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
me2Malic enzyme. (583 aa)    
Predicted Functional Partners:
fh
Fumarate hydratase.
  
 
 0.983
Mdh2
Malate dehydrogenase.
  
 0.964
LOC101173617
Malate synthase-like.
  
 
 0.959
pdhb
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.958
LOC101170426
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.956
LOC101170748
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.956
cs
Citrate synthase; Belongs to the citrate synthase family.
  
 0.953
mdhb
Malate dehydrogenase.
  
 0.951
mdh1
Malate dehydrogenase.
  
 0.951
LOC101165776
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.946
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.