Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
mtbpMDM2 binding protein. (882 aa)    
Predicted Functional Partners:
mdm2
MDM2 proto-oncogene.
    
 0.969
ticrr
Treslin_N domain-containing protein.
   
 0.881
topbp1
DNA topoisomerase II binding protein 1.
   
 
 0.853
mdm4
MDM4 regulator of p53; Belongs to the MDM2/MDM4 family.
    
 0.843
recql4
RecQ helicase-like 4.
   
 
 0.776
H2MDZ5_ORYLA
Ribonuclease P and MRP subunit p25, b.
      
 0.706
c11h1orf109
C19h1orf109 homolog (H. sapiens).
      
 0.699
cdc45
CDC45 cell division cycle 45 homolog (S. cerevisiae).
   
 
 0.697
LOC101167611
Mago homolog, exon junction complex subunit.
    
 0.665
drap1
DR1-associated protein 1 (negative cofactor 2 alpha).
      
 0.661
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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