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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtbpMDM2 binding protein. (882 aa)    
Predicted Functional Partners:
ticrr
Treslin_N domain-containing protein.
   
 0.725
mdm2
MDM2 proto-oncogene.
    
 0.640
ccnc
Cyclin C; Belongs to the cyclin family.
   
 0.626
recql4
RecQ helicase-like 4.
   
 
 0.612
LOC101156200
Von Willebrand factor A domain containing 5B2.
    
 
 0.563
c11h1orf109
C19h1orf109 homolog (H. sapiens).
      
 0.543
cdc45
CDC45 cell division cycle 45 homolog (S. cerevisiae).
   
 
 0.540
dbf4
DBF4 zinc finger.
   
 0.492
topbp1
DNA topoisomerase II binding protein 1.
   
 0.491
drap1
DR1-associated protein 1 (negative cofactor 2 alpha).
      
 0.482
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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