Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pros1Protein S. (678 aa)    
Predicted Functional Partners:
mertk
C-mer proto-oncogene tyrosine kinase a.
    
 0.986
LOC101158315
TYRO3 protein tyrosine kinase.
   
 0.982
AXL
AXL receptor tyrosine kinase.
   
 0.979
ggcx
Gamma-glutamyl carboxylase.
   
 0.972
proc
Protein C (inactivator of coagulation factors Va and VIIIa), a.
   
 0.954
LOC101174928
Coagulation factor VIII, procoagulant component; Belongs to the multicopper oxidase family.
   
 0.894
LOC101166425
Coagulation factor V; Belongs to the multicopper oxidase family.
   
 0.894
auts2
Activator of transcription and developmental regulator AUTS2 a.
      
 0.859
c5
Uncharacterized protein.
   
 
 0.851
serpind1
Serpin peptidase inhibitor, clade D (heparin cofactor), member 1; Belongs to the serpin family.
   
 
 0.847
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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