Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tdrd1Tudor domain-containing protein 1; Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of corr [...] (1141 aa)    
Predicted Functional Partners:
piwil2
Uncharacterized protein; Belongs to the argonaute family.
   
 0.956
piwil1
Uncharacterized protein; Belongs to the argonaute family.
   
 0.952
asz1
Ankyrin repeat, SAM and basic leucine zipper domain containing 1.
   
 0.907
ENSORLP00000040614
Tudor domain containing 12.
    
 0.892
pld6
Phospholipase D family, member 6.
   
  
 0.812
mov10l1
Uncharacterized protein.
   
 0.790
henmt1
HEN methyltransferase 1.
    
 0.765
fkbp6
Peptidylprolyl isomerase.
   
 
 0.765
H2MMA0_ORYLA
Tudor domain containing 9.
   
0.749
tdrkh
Tudor and KH domain containing.
   
0.689
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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