Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
serpinf2SERPIN domain-containing protein; Belongs to the serpin family. (476 aa)    
Predicted Functional Partners:
serpind1
Serpin peptidase inhibitor, clade D (heparin cofactor), member 1; Belongs to the serpin family.
  
 
0.900
LOC101170246
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.896
igfals
Insulin-like growth factor binding protein, acid labile subunit.
   
 
 0.837
cfi
Complement factor I; Belongs to the peptidase S1 family.
   
 0.794
stil
SERPIN domain-containing protein; Belongs to the serpin family.
  
 
0.788
LOC101168652
Alpha-2-HS-glycoprotein 2.
   
 
 0.776
plau
Plasminogen activator, urokinase a; Belongs to the peptidase S1 family.
    
 0.768
plau-2
Urokinase type plasminogen activator.
    
 0.768
plat
Uncharacterized protein.
    
 0.768
fga
Fibrinogen alpha chain.
   
 
 0.764
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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