gtf2b protein (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

gtf2b

General transcription factor IIB. (311 aa)

Predicted Functional Partners:

ercc3

0.996

gtf2f1

0.995

polr2a

0.993

polr2g

0.992

polr2d

0.986

gtf2e1

0.983

polr2h

0.981

LOC101159038

0.979

polr2b

0.977

POLR2E

0.976

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101159038	POLR2E	ENSORLP00000016388	ENSORLP00000019213	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	RNA polymerase II subunit E.	0.697
LOC101159038	ercc3	ENSORLP00000016388	ENSORLP00000005510	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	Excision repair cross-complementation group 3.	0.853
LOC101159038	gtf2b	ENSORLP00000016388	ENSORLP00000006167	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	General transcription factor IIB.	0.979
LOC101159038	gtf2e1	ENSORLP00000016388	ENSORLP00000025344	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	General transcription factor IIE, polypeptide 1, alpha.	0.935
LOC101159038	gtf2f1	ENSORLP00000016388	ENSORLP00000044821	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.917
LOC101159038	polr2a	ENSORLP00000016388	ENSORLP00000038121	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.685
LOC101159038	polr2b	ENSORLP00000016388	ENSORLP00000025492	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.668
LOC101159038	polr2d	ENSORLP00000016388	ENSORLP00000006639	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	Polymerase (RNA) II (DNA directed) polypeptide D.	0.829
LOC101159038	polr2g	ENSORLP00000016388	ENSORLP00000003930	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	Polymerase (RNA) II (DNA directed) polypeptide G-like.	0.860
LOC101159038	polr2h	ENSORLP00000016388	ENSORLP00000039282	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.760
POLR2E	LOC101159038	ENSORLP00000019213	ENSORLP00000016388	RNA polymerase II subunit E.	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.697
POLR2E	ercc3	ENSORLP00000019213	ENSORLP00000005510	RNA polymerase II subunit E.	Excision repair cross-complementation group 3.	0.944
POLR2E	gtf2b	ENSORLP00000019213	ENSORLP00000006167	RNA polymerase II subunit E.	General transcription factor IIB.	0.976
POLR2E	gtf2e1	ENSORLP00000019213	ENSORLP00000025344	RNA polymerase II subunit E.	General transcription factor IIE, polypeptide 1, alpha.	0.977
POLR2E	gtf2f1	ENSORLP00000019213	ENSORLP00000044821	RNA polymerase II subunit E.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.960
POLR2E	polr2a	ENSORLP00000019213	ENSORLP00000038121	RNA polymerase II subunit E.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
POLR2E	polr2b	ENSORLP00000019213	ENSORLP00000025492	RNA polymerase II subunit E.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
POLR2E	polr2d	ENSORLP00000019213	ENSORLP00000006639	RNA polymerase II subunit E.	Polymerase (RNA) II (DNA directed) polypeptide D.	0.999
POLR2E	polr2g	ENSORLP00000019213	ENSORLP00000003930	RNA polymerase II subunit E.	Polymerase (RNA) II (DNA directed) polypeptide G-like.	0.999
POLR2E	polr2h	ENSORLP00000019213	ENSORLP00000039282	RNA polymerase II subunit E.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.999