Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cd74CD74 molecule, major histocompatibility complex, class II invariant chain a. (282 aa)    
Predicted Functional Partners:
fau
40S ribosomal protein S30.
   
 0.999
rps3
Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
  
 0.998
rps18
Ribosomal protein S18.
  
 0.998
rps13
Ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family.
  
 0.998
rps8
40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family.
   
 0.998
rps15
Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.
  
 0.998
rps2
Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.
  
 0.998
rps25
40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family.
   
 0.998
rpsa
40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family.
  
 0.998
rps16
Ribosomal protein S16.
  
 0.998
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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