tsr1 protein (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

tsr1

TSR1 ribosome maturation factor. (834 aa)

Predicted Functional Partners:

bysl

0.999

ltv1

0.999

rrp12

0.997

nob1

0.996

dimt1

0.994

riok2

0.986

pno1

0.984

polr1b

0.982

riok1

0.973

tfb2m

0.966

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
bysl	dimt1	ENSORLP00000000305	ENSORLP00000011442	Bystin-like.	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.	0.990
bysl	ltv1	ENSORLP00000000305	ENSORLP00000001700	Bystin-like.	LTV1 ribosome biogenesis factor.	0.999
bysl	nob1	ENSORLP00000000305	ENSORLP00000030478	Bystin-like.	NIN1 (RPN12) binding protein 1 homolog.	0.999
bysl	pno1	ENSORLP00000000305	ENSORLP00000002947	Bystin-like.	RNA-binding protein PNO1; Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA. Belongs to the PNO1 family.	0.998
bysl	polr1b	ENSORLP00000000305	ENSORLP00000001089	Bystin-like.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.868
bysl	riok1	ENSORLP00000000305	ENSORLP00000010324	Bystin-like.	Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.	0.996
bysl	riok2	ENSORLP00000000305	ENSORLP00000010865	Bystin-like.	RIO domain-containing protein.	0.999
bysl	rrp12	ENSORLP00000000305	ENSORLP00000010908	Bystin-like.	Ribosomal RNA processing 12 homolog.	0.998
bysl	tfb2m	ENSORLP00000000305	ENSORLP00000014118	Bystin-like.	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.	0.963
bysl	tsr1	ENSORLP00000000305	ENSORLP00000006201	Bystin-like.	TSR1 ribosome maturation factor.	0.999
dimt1	bysl	ENSORLP00000011442	ENSORLP00000000305	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.	Bystin-like.	0.990
dimt1	ltv1	ENSORLP00000011442	ENSORLP00000001700	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.	LTV1 ribosome biogenesis factor.	0.977
dimt1	nob1	ENSORLP00000011442	ENSORLP00000030478	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.	NIN1 (RPN12) binding protein 1 homolog.	0.976
dimt1	pno1	ENSORLP00000011442	ENSORLP00000002947	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.	RNA-binding protein PNO1; Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA. Belongs to the PNO1 family.	0.901
dimt1	polr1b	ENSORLP00000011442	ENSORLP00000001089	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.735
dimt1	riok2	ENSORLP00000011442	ENSORLP00000010865	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.	RIO domain-containing protein.	0.926
dimt1	rrp12	ENSORLP00000011442	ENSORLP00000010908	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.	Ribosomal RNA processing 12 homolog.	0.939
dimt1	tsr1	ENSORLP00000011442	ENSORLP00000006201	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.	TSR1 ribosome maturation factor.	0.994
ltv1	bysl	ENSORLP00000001700	ENSORLP00000000305	LTV1 ribosome biogenesis factor.	Bystin-like.	0.999
ltv1	dimt1	ENSORLP00000001700	ENSORLP00000011442	LTV1 ribosome biogenesis factor.	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.	0.977