Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (397 aa)    
Predicted Functional Partners:
LOC101159747
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.986
LOC101162905
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.986
lamtor3
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.
   
 0.985
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
   
0.982
araf
A-Raf proto-oncogene, serine/threonine kinase.
   
0.982
braf
B-Raf proto-oncogene, serine/threonine kinase.
   
0.982
map3k8
Mitogen-activated protein kinase kinase kinase 8.
  
0.979
mos
V-mos Moloney murine sarcoma viral oncogene homolog; Belongs to the protein kinase superfamily.
  
 
 
0.927
map2k1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
  
  
0.901
LOC101157651
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.867
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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