pias4 protein (Oryzias latipes) - STRING interaction network

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pias4

Protein inhibitor of activated STAT, 4a. (503 aa)

Predicted Functional Partners:

sumo1

0.989

LOC101169703

0.984

ube2i

0.984

parp1

0.958

sumo2-2

0.925

sumo4

0.925

sumo2

0.904

brca1

0.901

tp53bp1

0.851

rnf8

0.839

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101169703	brca1	ENSORLP00000016945	ENSORLP00000005763	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Uncharacterized protein.	0.831
LOC101169703	parp1	ENSORLP00000016945	ENSORLP00000017176	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.821
LOC101169703	pias4	ENSORLP00000016945	ENSORLP00000006265	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Protein inhibitor of activated STAT, 4a.	0.984
LOC101169703	rnf8	ENSORLP00000016945	ENSORLP00000015004	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.658
LOC101169703	sumo1	ENSORLP00000016945	ENSORLP00000000767	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Small ubiquitin-related modifier.	0.993
LOC101169703	sumo2	ENSORLP00000016945	ENSORLP00000004077	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Small ubiquitin-related modifier.	0.937
LOC101169703	sumo2-2	ENSORLP00000016945	ENSORLP00000012260	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Small ubiquitin-related modifier.	0.930
LOC101169703	sumo4	ENSORLP00000016945	ENSORLP00000036220	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Small ubiquitin-related modifier.	0.930
LOC101169703	tp53bp1	ENSORLP00000016945	ENSORLP00000033455	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Tumor protein p53 binding protein, 1.	0.851
LOC101169703	ube2i	ENSORLP00000016945	ENSORLP00000045538	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.900
brca1	LOC101169703	ENSORLP00000005763	ENSORLP00000016945	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.831
brca1	parp1	ENSORLP00000005763	ENSORLP00000017176	Uncharacterized protein.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.946
brca1	pias4	ENSORLP00000005763	ENSORLP00000006265	Uncharacterized protein.	Protein inhibitor of activated STAT, 4a.	0.901
brca1	rnf8	ENSORLP00000005763	ENSORLP00000015004	Uncharacterized protein.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.853
brca1	sumo1	ENSORLP00000005763	ENSORLP00000000767	Uncharacterized protein.	Small ubiquitin-related modifier.	0.875
brca1	sumo2	ENSORLP00000005763	ENSORLP00000004077	Uncharacterized protein.	Small ubiquitin-related modifier.	0.758
brca1	sumo2-2	ENSORLP00000005763	ENSORLP00000012260	Uncharacterized protein.	Small ubiquitin-related modifier.	0.758
brca1	sumo4	ENSORLP00000005763	ENSORLP00000036220	Uncharacterized protein.	Small ubiquitin-related modifier.	0.758
brca1	tp53bp1	ENSORLP00000005763	ENSORLP00000033455	Uncharacterized protein.	Tumor protein p53 binding protein, 1.	0.998
brca1	ube2i	ENSORLP00000005763	ENSORLP00000045538	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.831