STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gfra1GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. (466 aa)    
Predicted Functional Partners:
gdnf
Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake.
    
 0.946
ret
Ret proto-oncogene receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.875
NRTN
Neurturin.
    
 0.844
nanos2
Nanos-type domain-containing protein; Belongs to the nanos family.
      
 0.647
zbtb16
PLZFa.
      
 0.627
fgfr2
Fibroblast growth factor receptor.
    
 0.579
LOC100049521
Fibroblast growth factor receptor 4.
    
 0.579
fgfr1
Fibroblast growth factor receptor.
    
 0.579
fgfr3
Fibroblast growth factor receptor.
    
 0.579
LOC101165069
Fibroblast growth factor receptor like 1a.
    
 0.579
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.