STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SMAD4Mothers against decapentaplegic homolog. (510 aa)    
Predicted Functional Partners:
smad2
Mothers against decapentaplegic homolog.
   
0.986
LOC101159109
Mothers against decapentaplegic homolog.
   
0.986
smad3
Mothers against decapentaplegic homolog.
   
0.985
LOC101169523
Mothers against decapentaplegic homolog.
   
0.984
LOC101160003
Mothers against decapentaplegic homolog.
   
0.982
smad1
Mothers against decapentaplegic homolog.
   
0.981
smad9
Mothers against decapentaplegic homolog.
   
0.980
ski
V-ski avian sarcoma viral oncogene homolog a.
    
 0.971
skil
SKI-like proto-oncogene a.
    
 0.970
smad7
Mothers against decapentaplegic homolog.
    
0.969
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.