STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAD4Mothers against decapentaplegic homolog. (510 aa)    
Predicted Functional Partners:
LOC101159109
Mothers against decapentaplegic homolog.
   
0.988
smad1
Mothers against decapentaplegic homolog.
   
0.982
LOC101160003
Mothers against decapentaplegic homolog.
   
0.981
LOC101169523
Mothers against decapentaplegic homolog.
   
0.979
smad9
Mothers against decapentaplegic homolog.
   
0.979
e2f4
E2F transcription factor 4.
    
 0.958
rbl1
Retinoblastoma-like 1 (p107).
   
 0.957
tfdp1
Transcription factor.
     
 0.954
lef1
Lymphoid enhancer-binding factor 1.
    
 0.946
smad2
Mothers against decapentaplegic homolog.
   
0.945
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.