Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
evx1Even-skipped homeobox 1. (375 aa)    
Predicted Functional Partners:
mfsd5
Major facilitator superfamily domain containing 5.
      
 0.636
SPRYD3
SPRY domain containing 3.
      
 0.628
LOC101156411
SPRY domain containing 3.
      
 0.628
LOC101170140
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.533
shh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
      
 0.527
LOC101157467
Peptidylprolyl isomerase.
      
 0.524
fkbp14
Peptidylprolyl isomerase.
      
 0.514
unc5a
Unc-5 netrin receptor A.
    
 
 0.499
mansc1-2
Parathyroid hormone-like hormone a.
      
 0.484
emx2
Empty spiracles homeobox 2.
  
   
 0.473
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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