STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dot1lHistone-lysine N-methyltransferase, H3 lysine-79 specific. (1578 aa)    
Predicted Functional Partners:
ubc
Ubiquitin B.
   
   0.868
rps27a
Ribosomal protein S27a.
   
   0.868
mllt6
MLLT6, PHD finger containing.
    
 
 0.863
mllt10
MLLT10 histone lysine methyltransferase DOT1L cofactor.
    
 
 0.863
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
   0.829
H2M970_ORYLA
Ubiquitin-like domain-containing protein.
    
   0.829
H3-3B
Histone H3; Belongs to the histone H3 family.
   
 0.804
setd2
SET domain containing 2, histone lysine methyltransferase.
   
 
 0.766
H2L503_ORYLA
Histone H3; Belongs to the histone H3 family.
   
 0.762
H2L5K1_ORYLA
Histone H3; Belongs to the histone H3 family.
   
 0.762
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.