Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
frmd3FERM domain containing 3. (622 aa)    
Predicted Functional Partners:
Psat1
Phosphoserine aminotransferase 1.
      
 0.510
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
    
 
 0.506
ENSORLP00000035023
Uncharacterized protein.
 
      0.475
LOC101172563
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
   
 0.473
cask
Uncharacterized protein; Belongs to the MAGUK family.
   
 0.473
sucla2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
      
 0.462
isca1
Iron-sulfur cluster assembly 1.
      
 0.462
LOC101166386
Fructosamine 3 kinase related protein; Belongs to the fructosamine kinase family.
      
 0.431
rasef
RAS and EF-hand domain containing.
      
 0.430
LOC101159669
Zgc:162879.
      
 0.430
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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