Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fbxo10F-box protein 10. (977 aa)    
Predicted Functional Partners:
cul1
Cullin 1b; Belongs to the cullin family.
   
 0.987
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.961
LOC101172920
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.754
CUL3
Cullin 3; Belongs to the cullin family.
   
 0.754
pde6d
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]
    
 
 0.730
acsl4
Acyl-CoA synthetase long chain family member 4a.
   
 
 0.641
H2MG95_ORYLA
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.631
acsl3
Uncharacterized protein.
   
 
 0.621
LOC101172360
Acyl-CoA synthetase long chain family member 3b.
   
 
 0.621
LOC101161115
TIP120 domain-containing protein.
   
 
 0.593
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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