Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
pde6cPhosphodiesterase. (853 aa)    
Predicted Functional Partners:
pde6g
Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.
   
 0.951
LOC101158106
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2.
   
 
 0.915
olgc6
Guanylate cyclase.
   
 0.818
olgc-r1
Guanylate cyclase.
   
 0.818
olgc9
Guanylate cyclase.
   
 0.818
olgc3
Guanylate cyclase.
   
 0.810
NT5E
5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family.
     
 0.803
NT5E-2
5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.
     
 0.803
LOC101168622
Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog a.
   
 
 0.801
LOC101167167
Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
   
 0.801
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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