STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wwp1WW domain containing E3 ubiquitin protein ligase 1. (960 aa)    
Predicted Functional Partners:
ubc
Ubiquitin B.
    
 0.866
rps27a
Ribosomal protein S27a.
    
  0.850
LOC101169984
Receptor protein-tyrosine kinase.
    
 0.842
egfr
Receptor protein-tyrosine kinase.
    
 0.842
ripk2
Receptor-interacting serine-threonine kinase 2.
    
 0.807
LOC101174746
E3 ubiquitin-protein ligase.
   
  0.800
LOC101167949
E3 ubiquitin-protein ligase.
   
  0.800
ube2l3
Ubiquitin-conjugating enzyme E2L 3b; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.786
LOC101155128
Spartin b.
    
 
 0.784
LOC101165589
Agouti signaling protein, nonagouti homolog (mouse) 2b.
      
 0.751
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.