Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sp7Sp7 transcription factor. (460 aa)    
Predicted Functional Partners:
LOC100529176
Collagen, type X, alpha 1a.
    
 0.827
runx2
Runt-related transcription factor.
    
 0.801
LOC101164922
Cathepsin K; Belongs to the peptidase C1 family.
    
 
 0.796
trps1
Trichorhinophalangeal syndrome I.
    
 0.734
sost
Sclerostin.
    
 
 0.726
nkx6-1
NK6 homeobox 1.
      
 0.692
opga
TNFR-Cys domain-containing protein.
      
 0.609
fli1
Fli-1 proto-oncogene, ETS transcription factor a.
   
 0.599
col1a2
Collagen, type I, alpha 2.
    
 0.596
phex
Phosphate regulating endopeptidase homolog, X-linked.
   
  
 0.582
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.