STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ntrk2Tyrosine-protein kinase receptor. (745 aa)    
Predicted Functional Partners:
bdnf
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
   
 0.888
LOC101157368
Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.
    
 0.819
LOC101164147
Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family.
    
 0.790
LOC101170271
Nerve growth factor receptor a (TNFR superfamily, member 16).
   
 0.762
grb2
Growth factor receptor-bound protein 2b.
    
 0.694
sqstm1
Sequestosome 1.
    
 0.686
LOC101174825
Fibroblast growth factor receptor substrate 3.
    
 0.669
frs2
Fibroblast growth factor receptor substrate 2b.
    
 0.669
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
  0.628
LOC101167946
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.
    
 0.585
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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