Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101164834FH2 domain-containing protein. (377 aa)    
Predicted Functional Partners:
SPIRE1
Spire type actin nucleation factor 1.
    
 0.858
ENSORLP00000044450
Myosin VB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.803
LOC101166499
Profilin; Belongs to the profilin family.
    
 0.724
Myo5b
Myosin VB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.684
LOC101161232
Profilin; Belongs to the profilin family.
    
 0.634
RAB11A
RAB11A, member RAS oncogene family.
    
 0.565
CDC42
Cell division cycle 42.
    
 0.545
LOC101164400
Uncharacterized protein.
    
 0.545
suox
Sulfite oxidase.
      
 0.535
JMY-2
Junction mediating and regulatory protein, p53 cofactor; Belongs to the globin family.
    
 
 0.528
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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