Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
grem2Gremlin 2, DAN family BMP antagonist a. (192 aa)    
Predicted Functional Partners:
Grem1
Gremlin 1a, DAN family BMP antagonist.
  
 
 
0.952
GREM1
Gremlin.
  
  
 
0.903
bmp4
Bone morphogenetic protein 4.
     
 0.858
bmp2
TGF_BETA_2 domain-containing protein.
     
 0.835
LOC101163346
Bone morphogenetic protein 16.
     
 0.835
LOC101170375
Anti-dorsalizing morphogenic protein.
     
 0.795
bmp6
Bone morphogenetic protein 6.
     
 0.748
bmp5
Bone morphogenetic protein 5.
     
 0.748
LOC101173146
Bone morphogenetic protein 7b.
     
 0.748
gdf5
Growth differentiation factor 5.
     
 0.748
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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