Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101163464SERPIN domain-containing protein; Belongs to the serpin family. (403 aa)    
Predicted Functional Partners:
LOC101170246
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.754
arpc2
Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
 
      0.571
mgst1
Microsomal glutathione S-transferase 1.2.
   
  
 0.534
LOC101171566
Ceruloplasmin; Belongs to the multicopper oxidase family.
   
 0.530
ENSORLP00000034462
Uncharacterized protein; Belongs to the multicopper oxidase family.
   
 0.530
rbp4
Retinol binding protein 4, plasma; Belongs to the calycin superfamily. Lipocalin family.
   
  
 0.527
LOC101161031
Choline kinase alpha.
      
 0.506
rnf141
Ring finger protein 141.
      
 0.501
GLS
Glutaminase.
     
 0.499
LOC101174762
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.497
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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