STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
angptl4Angiopoietin-like 4. (469 aa)    
Predicted Functional Partners:
dusp8
Dual specificity phosphatase 8a.
      
 0.613
atf2
Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.
      
 0.591
LOC101166566
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
   
  
 0.570
vegfb
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
     
 0.563
LOC101174288
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
   
  
 0.561
pdgfc
Platelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family.
      
 0.559
PTPN14
Protein tyrosine phosphatase non-receptor type 14.
    
 0.478
ech1
Enoyl CoA hydratase 1, peroxisomal; Belongs to the enoyl-CoA hydratase/isomerase family.
      
 0.447
colec11
Collectin sub-family member 11.
    
 0.434
pik3r5
Phosphoinositide-3-kinase, regulatory subunit 5.
      
 0.426
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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